TriStar Centennial Children’s Hospital in Nashville is at the forefront of a major breakthrough in treating sickle cell disease with a FDA‑approved gene‑editing therapy. The treatment, exagamglogene autotemcel (exa‑cel), is a CRISPR‑based cell therapy that can potentially cure the disease in eligible patients. If you or a loved one in Middle Tennessee is eligible, contacting TriStar Centennial Children’s Hospital or the Sarah Cannon Transplant and Cellular Therapy Program is the next step to learn more.