The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated $2,825,000 to the ACC, funding 63 research projects. 100% of all participant-raised dollars are donated directly to cancer research.

View Breakthrough Challenge 2025 Images
Our 2025 Fundraising Goal
$340,350
Raised of $300,000
Thank You to our donors, sponsors, volunteers, and riders!
Breakthroughs in Action

Thank You To Our Fundraisers!
Top Individuals
View AllBruce Levine
$42,195.00 raised of $30,000.00
Lynn Schuchter
$34,585.76 raised
Bo Ebby
$18,300.00 raised of $15,000.00
William Wilson
$13,690.00 raised of $1,000.00
Lou Starzl
$12,575.00 raised of $12,500.00
Top Teams
View AllMission Melanoma
$64,745.76 raised of $10,000.00
Keystone State Ride
$56,228.53 raised of $30,000.00
CARs Pedaling For Cures
$49,058.69 raised of $50,000.00
Team BC
$30,303.53 raised of $25,000.00
Team Krieger
$23,675.00 raised of $10,000.00
Donate To an Indvidual or a Team
Donate NowJoin Us to Make a Difference!
